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Journal of Veterinary Diagnostic Investigation, Vol 2, Issue 3, 217-221
Copyright © 1990 by American Association of Veterinary Laboratory Diagnosticians


Articles

Pulmonary edema and hydrothorax in swine produced by fumonisin B1, a toxic metabolite of Fusarium moniliforme

LR Harrison, BM Colvin, JT Greene, LE Newman, and JR Cole Jr

Veterinary Diagnostic and Investigational Laboratory, University of Georgia, Tifton 31794.

Pulmonary edema and hydrothorax were observed in mature swine that died approximately 5 days after consuming corn screenings. These postmortem observations were reproduced in younger swine (16-24 kg) that died within 1 week when fed the corn screenings under experimental conditions. Additionally, pulmonary edema and hydrothorax occurred in a pig (7.1 kg) that died after receiving 4 daily intravenous injections of fumonisin B1. A fungus was isolated from the corn screenings that is identical to Fusarium moniliforme MRC-826 in colony morphology and under microscopic examination.


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