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Journal of Veterinary Diagnostic Investigation, Vol 18, Issue 4, 418-422
Copyright © 2006 by American Association of Veterinary Laboratory Diagnosticians

Articles

Brachyspina syndrome in a Holstein calf

JS Agerholm, F McEvoy, and J Arnbjerg

Department of Veterinary Pathobiology, Royal Veterinary and Agricultural University, Bulowsvej 17, DK-1870 Frederiksberg C, Denmark. jager@kvl.dk

A stillborn premature Holstein calf was necropsied. The calf had severely reduced body weight and shortening of the vertebral column. The limbs appeared long and thin. Radiography and computer tomography scanning were performed, demonstrating malformation of the vertebral column. In addition, malformation of the kidneys, testicles, and heart was found at necropsy. Histologically, absence or incomplete development of intervertebral discs and complete or partial fusion of the epiphyses of adjacent vertebrae were found. In some areas, diaphyses of adjacent vertebrae were fused due to absence of epiphyses and intervertebral discs. Disturbed ossification of epiphyses in the appendicular skeleton was also present. The etiology of this syndrome was not identified. An inherited cause is possible due to a close relationship between the parents.


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