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Journal of Veterinary Diagnostic Investigation, Vol 17, Issue 3, 245-248
Copyright © 2005 by American Association of Veterinary Laboratory Diagnosticians

Articles

Variation among pathologists in histologic grading of canine cutaneous mast cell tumors

NC Northrup, BG Harmon, TL Gieger, CA Brown, KP Carmichael, A Garcia, KS Latimer, JS Munday, PM Rakich, LJ Richey, NL Stedman, AL Cheng, and EW Howerth

Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.

Ten veterinary pathologists at 1 veterinary institution independently assigned histologic grades to the same 60 canine cutaneous mast cell tumors (MCTs). There was significant variation among pathologists in grading the MCTs (P < 0.001). The probability of assigning a low grade was significantly higher for the pathologists in this study who use a published reference for histologic grading of canine cutaneous MCTs that allows subcutaneous MCTs or MCTs with mitotic figures to be included in the low-grade category (P < 0.0001 and P < 0.0001, respectively).


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