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Journal of Veterinary Diagnostic Investigation, Vol 13, Issue 4, 346-348
Copyright © 2001 by American Association of Veterinary Laboratory Diagnosticians

Case Reports

Digital papillomatosis in a confined Beagle

BM Debey, M Bagladi-Swanson, S Kapil, and FW Oehme

Department of Diagnostic Medicine, Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan 66506, USA.

Papillomavirus-induced papillomas were diagnosed on multiple digits of all 4 feet of a young Beagle. No other cutaneous or oral involvement was identified. Papillomavirus antigen was confirmed by immunoperoxidase localization within keratinocyte nuclei. In addition to the typical basophilic intranuclear inclusions associated with papillomavirus infections, keratinocytes within the papillomas contained large, eosinophilic cytoplasmic inclusions that previously have been described in a Boxer with cutaneous lesions associated with a papillomavirus infection. The papillomas in this Beagle regressed completely within 2 months of the initial diagnosis.




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